Targeted, imaging-based spatial profiling at single-cell and subcellular resolution.
Xenium is a next-generation in situ transcriptomics platform from 10x Genomics. Instead of sequencing the whole transcriptome, it uses multiplex imaging and decoding cycles to map RNA molecules directly in intact tissue sections.
Unlike sequencing-based methods, Xenium does not require NGS. Instead, it uses multiplex rounds of fluorescent imaging to directly detect RNA molecules in intact tissue sections at single-cell and subcellular resolution.
Feature | Details |
Sample Types | FFPE and fresh-frozen tissue sections |
Panel Options | Ready-to-use (breast, brain, lung, mouse brain), pan-cancer, or custom (add 1–100 genes) |
Throughput | Each slide covers 12 × 24 mm, fits 2–3 sections, and two slides can run in paralle |
Xenium is ideal when you already know the targets you want to validate and need high-resolution spatial context.
Use Xenium for:
Marker validation after scRNA-seq or Visium discovery.
Clinical or translational cohorts with FFPE tissues.
Precise localization of RNA molecules in tumor or neural microenvironments.
RNA + protein co-detection for immune profiling (27-plex subpanels).
Choose Visium when you need whole-transcriptome discovery. Still deciding between Xenium and Visium HD? Read our blog: 10x Genomics Visium HD vs. Xenium – Which to Choose?
Extensive experience in single-cell and spatial transcriptomics, with a global network of laboratories and PhD-level technical support.
Successfully conducted 17,000+ single-cell experiments across 2,000+ tissue types.
Contributed to 370+ scientific publications, widely recognized in single-cell and spatial transcriptomics.
Client trust and satisfaction are our top priorities, serving as the key measure of our success.
We actively engage with researchers, offering customized sequencing solutions tailored to their specific needs.
Diverse single-cell and spatial sequencing solutions tailored to various research needs.
Strong partnerships with top-tier omics platforms, ensuring access to cutting-edge technologies.
Capable of handling projects of all scales, from pilot studies to large-scale research initiatives.
With lab operations in the U.S., Europe, and Asia, we provide responsive support for international projects and multi-site studies. Coordinated logistics ensure timely delivery and sample stability—no matter where your research takes place.
Sample Type | Tissue Size | Embedding Method | Section Thickness | Shipping Method |
Fresh Tissue Sample | ≤8mm×6mm | OCT or Leica Gel | 10μm | No special requirements |
Frozen Tissue Sample | ≤8mm×6mm | OCT or Leica Gel | 10μm | Stored at -80℃ |
Paraffin-Embedded Sample (FFPE) | ≤8mm×6mm | Paraffin | 5μm | Shipped at 4℃ |
Singapore Global Headquarters: 112 ROBINSON ROAD #03-01
Germany: Arnold-Graffi-Haus / D85 Robert-Rössle-Straße 10 13125 Berlin
United States: 2 Goddard, Irvine, CA 92618
Hong Kong: Room 618, Building 6, Phase One, Hong Kong Science Park, No. 6 Science Park West Avenue, Pak Shek Kok, New Territories, Hong Kong
Singapore Global Headquarters: 112 ROBINSON ROAD #03-01
Germany: Arnold-Graffi-Haus / D85 Robert-Rössle-Straße 10 13125 Berlin
United States: 2 Goddard, Irvine, CA 92618
Hong Kong: Room 618, Building 6, Phase One, Hong Kong Science Park, No. 6 Science Park West Avenue, Pak Shek Kok, New Territories, Hong Kong
Singapore Global Headquarters: 112 ROBINSON ROAD #03-01
Germany: Arnold-Graffi-Haus / D85 Robert-Rössle-Straße 10 13125 Berlin
United States: 2 Goddard, Irvine, CA 92618
Hong Kong: Room 618, Building 6, Phase One, Hong Kong Science Park, No. 6 Science Park West Avenue, Pak Shek Kok, New Territories, Hong Kong
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